The year is 1965 and the Spring Fling Talent Show is in the works at Mississippi College for women. As a joke, Delta Ballou puts the names of her three best friends on the list of performers. Rising to the challenge, the Delta Belles win the talent show, and go on to perform at protests and voter registration rallies. Twenty-five-years later the recently widowed Delta is asked to get the Belles together to perform at their college reunion, which turns out to be much more than an opportunity to relive the past.